منابع مشابه
Fibronectin for branching
Fibronectin for branching ranched organs are shaped when epithelia make their own paths, according to a study by Takayoshi Sakai, Melinda Larsen, and Kenneth Yamada (National Institutes of Health, Bethesda, MD). The pathmaker in this process is fibronectin (FN), which tells cells to let go of their neighbors and instead grab hold of the underlying matrix. Organs such as the lung and kidney gain...
متن کاملCell and fibronectin dynamics during branching morphogenesis.
Branching morphogenesis is a dynamic developmental process shared by many organs, but the mechanisms that reorganize cells during branching morphogenesis are not well understood. We hypothesized that extensive cell rearrangements are involved, and investigated cell migration using two-color confocal time-lapse microscopy to image cell and extracellular-matrix dynamics in developing salivary gla...
متن کاملA Local Branching Approach for the Set Covering Problem
The set covering problem (SCP) is a well-known combinatorial optimization problem. This paper investigates development of a local branching approach for the SCP. This solution strategy is exact in nature, though it is designed to improve the heuristic behavior of the mixed integer programming solver. The algorithm parameters are tuned by design of experiments approach. The proposed method is te...
متن کاملa local branching approach for the set covering problem
the set covering problem (scp) is a well-known combinatorial optimization problem. this paper investigates development of a local branching approach for the scp. this solution strategy is exact in nature, though it is designed to improve the heuristic behavior of the mixed integer programming solver. the algorithm parameters are tuned by design of experiments approach. the proposed method is te...
متن کاملThe fibronectin receptor is organized by extracellular matrix fibronectin: implications for oncogenic transformation and for cell recognition of fibronectin matrices
Cells interact with extracellular fibronectin (FN) via adhesive fibronectin receptors (FNRs) that are members of the very late antigens (VLAs) subgroup of the integrin family. In stationary fibroblasts, the FNR is highly organized and distributed identically to extracellular FN fibrils. However, in highly migratory neural crest cells and embryonic somatic fibroblasts, this organization is lost ...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2003
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb1621rr1